Daniel is currently a Postdoctoral Researcher under Dr. Gert von Helden at the Fritz Haber Institute in Berlin, Germany.
Daniel's research in the Beauchamp group focused on unique chemical processes occurring at the liquid/vapor interface and gas-phase free radical chemistry of biomolecules. He developed and studied both novel chemical reagents and unique instrumental methods to explore these avenues of research. His projects in the group include:
-- Implementing novel soft ionization techniques that generate gas-phase ions via ejection of small droplets from a liquid surface into a mass spectrometer, providing a method to analyze heterogeneous reactions occurring at a planar liquid/vapor interface. This work was done in collaboration with Byoungsook Goh, a summer researcher in the group from Gwanju Institute of Science and Technology, and Lingtao Wang of the Kim group at the University of Southern California. This work was published in Analytical Chemistry. [link]
-- Exploring the effects of pH changes at the air/water interface on chemical reactions occurring in this region via field-induced droplet ionization mass spectrometry (FIDI-MS). Results suggest that the pH at the air/water interface is highly sensitive to the presence of gaseous acids and bases.
-- Utilizing microliter droplets as photochemical reactors to study reactions relevant to aqueous tropospheric aerosols. Working with Matt Coggon in the Seinfeld group, the oxidation of model atmospheric organics by photo-Fenton chemistry is examined.
-- Collaborating with the Flagan and Seinfeld groups at Caltech to develop new ion mobility technologies and apply them to biomomlecules. This work is being done in collaboration with Wilton Mui, a joint graduate student of the Flagan and Seinfeld groups. This work was published in Analytical Chemistry. [link]
-- Understanding the free radical chemistry occurring at serine and threonine residues in peptides that leads to unique dissociation pathways at these residues. These reactions also exemplify the strong influence of subtle alterations in the free energy landscape in dictating the products of these low-barrier reactions. This work was published in the Journal of Physical Chemistry A. [link]
-- Utilizing gas-phase free radical chemistry to improve the analysis of oligosaccharides. The low activation energy associated with free radical-initiated dissociation of these biomolecules provides extensive sequence coverage. It is imperative to elucidate the mechanism and energetics involved in these processes to improve the technique. Jinshan Gao was the lead researcher on this project. This work was published in the Journal of the American Chemical Society. [link]
Beauchamp Research Group